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Immunohistochemical detection of p53 and progerin, were performed on paraffin sections (3 m), and subsequent sections were exposed to horseradish peroxidase (HRP)-antibody colored with DAB, and visualized by microscopy (BX51, Olympus, Japan)
The skin tightening benefits of growth hormone elevation become more evident
The ferroptotic process engages multiple biological functionssuch as iron metabolism, lipid metabolism, oxidative stress, mevalonate signaling, transsulfuration pathways, heat shock protein activation, glutamate/cystine transport, and GSH biosynthesis