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Eur J Clin Pharmacol 34 : 7782

Symptoms of low B12 can include: Tiredness- this is one of the most common symptoms Pale appearance, palpitations, and shortness of breath (if anaemia is present) A smooth tongue Constipation, diarrhoea and reduced appetite Low mood, reduced concentration and memory problems Nerve damage- this can lead to weaknesss, tingling and numbness How is Vitamin B12 deficiency diagnosed

Exp Gerontol 80:4350 Shao D et al (2023) Dietary Pyrroloquinoline quinone improvement of the antioxidant capacity of laying hens and eggs are linked to the alteration of Nrf2/HO-1 pathway and gut microbiota