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NAD as a substrate for NAD-consuming enzymes The niacin coenzyme, NAD, is the substrate (reactant) for at least four classes of enzymes

Furthermore, adaptive mutations in NS3 and NS5B map to surface residues distant from the enzyme active sites, suggesting that these changes are likely to affect interactions between NS proteins and/or cellular factors

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Osoby z chorobami przewlekymi, takimi jak choroba Wilsona, problemy wtrobowe czy nerkowe, wymagaj indywidualnej oceny ryzyka i korzyci przed rozpoczciem terapii