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MIA, an inhibitor of glyceraldehyde-3-phosphate dehydrogenase, can disrupt chondrocyte glycolysis and ultimately lead to cell death, thereby contributing to cartilage degradation, subsequent alterations in subchondral bone, and the development of osteophytes 25,34

Its value is in identifying functional pathway abnormalities that may deserve further investigation or nutritional support

Peptide therapy sits somewhere between doing nothing and supplementation and those more advanced hormone therapies

Results showed that BPC-157 apparently reduced the cell number in the G0/G1 phase in a dose-dependent manner compared with the number in the control group (Figure 4B)