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Reducing the risk of metabolic diseases: Inhibiting NNMT may counteract the adverse metabolic changes associated with obesity, such as fatty liver disease

Negative effects are rare but may include: Mild discomfort at the injection site, temporary diarrhea, allergic reactions, or rash

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Furthermore, this trend toward increased alpha diversity in the obese groups placed on an LD that had consequently experienced weight loss aligns with clinical observations, where low gene richness has been associated with increased adiposity, insulin resistance, and dyslipidemia 70 while increased gene richness has been observed following dietary intervention in obese and overweight individuals 71