There is the increased pressure in the superior sagittal sinus presenting with the systemic arterial and venous thrombosis, severe brain and peripheral disturbances, cardiac dysfunction, lung congestion, kidney congestion, liver failure, portal and caval hypertension, aortal hypotension and hemorrhagic lesions in gastrointestinal tract, especially in the stomach and duodenum
However, these accounts remain personal experiences, not peer-reviewed clinical trials
The term mucoadhesion is commonly used for materials that bind to the mucin layer of a biological membrane
First, human amylin is aggregation-prone: at pharmaceutical concentrations it readily forms amyloid fibrils, the same class of deposits studied in the context of pancreatic islet pathology