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The detection window for these tests varies, with cotinine being detectable in: Urine for up to 20 days in regular users Blood for up to three weeks Saliva for up to 14 days in heavy smokers Hair for up to 90 days, reflecting long-term nicotine use These tests are utilized in various settings for different purposes: Smoking Cessation Programs Measure nicotine and cotinine levels to estimate pre-quit nicotine consumption

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