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It was first isolated in human plasma in 1973, and subsequent decades of research have revealed a mechanism that goes considerably beyond simple collagen stimulation

However, with IBD-current biologic therapies, all these mean some patients primary non-responders, experience a loss of response, intolerance or side effects, defining the urgent unmet need for novel treatments (13, 14)

Appropriate laboratory monitoring should be individualized according to the peptide prescribed, the patient's medical history, and current clinical practice guidelines, so what gets tested will not look identical for every compound