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As many of these transmembrane receptors are dimerized or heterodimerized by the interaction with cognate ligands to activate signalling pathways 1,38 , the methodology reported here is applicable to the design and synthesis of such artificial agonists

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This is attributed to its ability to stimulate the production of growth factors, promote angiogenesis (the formation of new blood vessels), and elevate the levels of other proteins that support tissue regeneration

The actual figure is likely much higher