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Zepbound: FDA-approved for weight management and moderate to severe obstructive sleep apnea

In the permeation assay, the tumor spheroids were exposed to a constant drug concentration, which was obtained after 24 h of permeation through the BBB and drug accumulation in the brain compartment

For the metabolomic analysis, 100 L of serum were mixed with 400 L of extraction solvent (methanol:acetonitrile:acetone = 1:1:1, v/v)

Previous studies have confirmed the roles of GSH as antioxidant constituents (enzymatic, non-enzymatic, or suitable organic solutes or osmoprotectants) and as a downstream component of signal transduction pathways under stress circumstances [35, 37, 38]