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Similar dysbiotic changes are observed in the respiratory and gastrointestinal systems, where smoking impairs mucosal immunity, increases oxidative stress, and compromises barrier integrity, thereby enhancing susceptibility to chronic diseases

DETOXICATED TOBACCO Article in Scientific American November 11, 1876 A correspondent, referring to our recent article A Cigar Scientifically Dissected, asks whether there is not some method whereby tobacco can be rendered innocuous and yet have its agreeable aroma preserved