Protocol (density gradient only) 1
Adv Pediatr 33:95126 Gretz N, Manz F, Augustin R, Barrat TM, Bender-Gotze C, Brandis M, Bremer HJ, Brodehl J, Broyer M, Bulla M, Callis L, Chantler C, Diekmann L, Dillon MJ, Egli F, Ehrich JH, Endres W, Fanconi A, Feldhoff C, Geisert J, Gekle D, Gescholl-Bauer B, Grote K, Gruttner R, Hagge W, Haycock CB, Hennemann H, Klare B, Leupold D, Lohr H, Michalk D, Oliveira A, Ott F, Pistor K, Rau J, Scharer K, Schindera F, Schmidt H, Schulte-Wissermann H, Verrier-Jones K, Weber HP, Willenbockel U, Wolf H (1983) Survival time in cystinosis
conducted a retrospective cohort study involving 20975 patients (4195 GD patients and 16780 non-GD patients) and discovered that GD and GD treatment are associated with an increased risk of depression in Asian patients ( Although our screening results have already supported a strong link between GD and depression, the number of current clinical studies available remains very limited
Low concentrations (1-2mM) of other additives such as Mg2+ or Ca2+ in Solution B can also be maintained constant in the gradient by inclusion in Solution A at 3-6 mM