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250 In fact, this modest selectivity of Ec ZntR has been exploited in the selection of engineered ZntR mutants capable of detecting xenobiotics 329,333,334 that are subsequently leveraged in the design of whole cell biosensors (Section 3.4)

The test product was then applied at varying concentrations (0.64, 3.2, 16, 80 M) to mouse macrophages for 24 h, and at concentrations of 3.2, 16, and 80 M to HFDPCs, followed by incubation for 24, 48, or 72 h

Lipid metabolic reprogramming in tumor microenvironment: From mechanisms to therapeutics