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Additionally, there was a loss of SC cells in human anterior segments (Santas et al., 2003) possibly resulting from a disruption in cell-cell adhesions since HepII treatment disrupted AJs in HTM cultures ( The composition of the ECM can affect the ability of the HepII domain and 41 integrin to disrupt the contractile properties of HTM cells (Figure 2)

Oxidative Stress, Mycotoxin Path to Cell's and System's Dysfunction Obstruction of the arteries (supplying blood to different tissues), defined as arterial dysfunction, is mainly the buildup of oxidative reactions and calcium and inflammatory deposits restoring each other (46)

[DOI] [PubMed] [Google Scholar] 196.Dimitriadis F., Kaltsas A., Zachariou A., Mamoulakis C., Tsiampali C., Giannakis I., Paschopoulos M., Papatsoris A., Loutradis D., Tsounapi P., et al