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Skin Pharmacology and Physiology (2014)

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10 L of isotonic saline containing 100 g/mL Nle-YI-(6) aminohexanoic amide as an internal standard is added to each sample on ice

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Tumor angiogenesis often results in a low-pH and hypoxic TME, which eventually limits drug efficacy

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Smaller improvements were seen through week 52

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