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The recent development of a robust Cu II -specific small molecule sensor strongly suggests that Cu II , rather than Cu I , mediates at least some of these Cu-dependent signaling processes described to date

Insulin promotes protein synthesis by muscle, and decreased blood insulin levels, during fasting for example, result in net proteolysis and release of amino acids from muscle into the blood

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J Inorg Biochem 153:112 Solovyev N, Drobyshev E, Bjrklund G, Dubrovskii Y, Lysiuk R, Rayman MP (2018) Selenium, selenoprotein P, and Alzheimers disease: is there a link