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Brezova V, Valko M, Breza M, Morris H, Telser J, Dvoranova D, Kaiserova K, Varecka L, Mazur M, Leibfritz D (2003) Role of radicals and singlet oxygen in photoactivated DNA cleavage by the anticancer drug camptothecin: an electron paramagnetic resonance study

Specifically, FIN56 induced ferroptosis by inhibiting GPX4, which led to increased lipid peroxidation and reduced cell viability

It stands for insulin like growth factor 1. Its technically an anabolic peptide hormone that has the role of stimulating growth and to a lesser degree supporting maintenance of normal blood sugar levels and a healthy metabolism

In contrast, MAZ51 treatment does not affect the villus capillary network, Esm1-CreERT2 -controlled GFP expression, or SOX17 signal (Fig