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Larsson A, Mattsson B, Wauters EA, van Gool JD, Duran M, Wadman SK

Consistent results were observed in a subanalysis of OS by high-dose steroid use in the durvalumab arm among participants who experienced an imAE, and interpretation of these results is again limited by the small number of participants within each subgroup

Initially, the alterations in intracellular protein concentrations post-treatment were assessed, and the principal component analysis (PCA) outcomes demonstrated a notable divergence in protein expression between the D-CuP-treated group and the PBS-treated control group (Fig

Firstly, we verified across a panel of normal and cancer cell lines with differing p53 status (Supplementary Table 1) that treatment with a lethal dose of APR-246 resulted in higher intracellular ROS (Fig