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This hyper ECD motion was propagated to the receptor TMD, with motions within TMs 3 and 7, creating a wider TM pocket that also influences the positioning of the N-terminus of the Cagri peptide (Fig

However, larger and long-term studies are warranted to generate more evidence

[2] Cell Line:PHGDH-dependent (MDA-MB-468, BT-20, HCC70, HT1080, MT-3) and PHGDH-independent (MDA-MB-231, ZR-75-1, SK-MEL-2) human cancer cell lines Concentration:Dose-response concentrations Incubation Time:4 days Result:Exhibited EC 50 values of 8-16 M for PHGDH-dependent cell lines

Dynamic gene and protein expression patterns of the autism-associated met receptor tyrosine kinase in the developing mouse forebrain