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doi: 10.1136/gutjnl-2024-332429 38 ShuningCYuJJiaoZPanLMaoyuLYiZet al

Fat tissue contributes to estrogen production, particularly after menopause

This combination approach delivers results faster than either method alone

Community sources describe starting conservatively at 0.25 mg 3x weekly (0.75 mg total weekly) for the first 2-4 weeks the dual GLP-1/GIP mechanism can cause more intense initial GI side effects than single-target agonists