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Results Individuals carrying an APP pathogenic genetic variant harbor a metabolically dysfunctional subset of CD38-expressing CD4 + T cells prior to symptom onset In the present study, we focused on individuals of a newly described highly consanguineous family, belonging to a minority ethnic group in northern Israel

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The idea that antibiotics can reduce the effects of microbiota and their metabolites on host metabolism via the gutliver axis is the foundation for their use in the treatment of MASLD