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Unknown Long-Term Effects & Lack of Human Data: Perhaps the biggest concern is simply that we dont know all the effects of BPC-157 in humans

Dasgupta, S., Hoque, M

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Interestingly, TFR1 had been previously identified as the major cell surface receptor for IgA1 binding in renal mesangial cells and its overexpression has been correlated with the proliferation of mesangial cells in IgAN patients [269,270,271]