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Even though vitiligo is the most direct example, other autoimmune disorders, especially those affecting the thyroid, can disrupt the hormonal signals that regulate melanin production and speed up the appearance of the first gray hairs

In the human healthy intestine, the most representative bacterial phyla are Firmicutes and Bacteroides, followed by Proteobacteria, Actinomyces, Fusobacteria and Verruciformes [12, 30, 31]

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