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doi: 10.1073/pnas.051618798 97

Metformin has been identified to significantly improve angiogenesis in PCOS

Wang K, Jiang H, Li W, Qiang M, Dong T, Li H

Despite these mechanistic strengths, the paucity of large-scale monotherapy trials and limited long-term outcome data constrain definitive conclusions regarding its independent antidepressant efficacy