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Acknowledgements This work was supported by a National Health and Medical Research Council (NHMRC) of Australia Centres for Research Excellence Grant #1040947 (W.A.P.), a Translational Research Project Grant (TRP15012) from the Victorian Government Department of Health and Human Services through the Victorian Cancer Agency (W.A.P., N.J.C., C.P.D.), and a Peter MacCallum Cancer Foundation New Investigator grant (D.S.L.)

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