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This not only enhances drug efficacy but also reduces the likelihood of drug resistance [82]

References Int J Mol Sci (MDPI) Overview of Epitalon: Highly Bioactive Pineal Tetrapeptide with Promising Properties (2025) PMC/Biogerontology Epitalon increases telomere length in human cell lines through telomerase upregulation Neuroendocrinology Letters (PubMed) Synthetic tetrapeptide Epitalon restores neuroendocrine regulation in senescent monkeys Bull Exp Biol Med (PubMed) Geroprotective effect of epithalamine in elderly with accelerated aging (12-year RCT) Alzheimers Drug Discovery Foundation Epithalamin/Epithalon Cognitive Vitality Report (mechanisms, dosing, safety) JPT Peptide Technologies Peptide Stability: How Long Do Peptides Last

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In contrast, compared with that in the control group, the recognition index significantly increased in both the combination group ( P = 0.0198