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Many users experience reduced stiffness and improved mobility, allowing them to engage in physical activities without discomfort

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Vascular endothelial growth factor increases and induces the translocation of glucose transporter-1 to the cell membrane at the BBB, which promotes angiogenesis and decreases the expression of inter-endothelial tight junction proteins, such as occludin and zonula occludens-1 [73], thus causing BBB leakage

The meta-analysis used both random-effects and fixed-effects models to evaluate pooled risk ratios (RRs) and 95% confidence intervals (CIs)