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Description

Herein, we review outcomes from recent mouse models where gut permeability was altered by direct and indirect effects of manipulating mucosal barrier-associated proteins, to highlight the significance of mucosal permeability and the non-barrier-related roles of these proteins in regulating chronic mucosal inflammatory conditions

Key findings 8.6.1

The extracellular matrix is a dynamic scaffold that provides structural support while also serving as a reservoir of growth factors and signalling molecules