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Ischemia-reperfusion injury occurs in a variety of conditions including shock, vascular surgery, strangulated bowel, trauma, intestinal volvulus, and intestinal transplantation, leaving both human and veterinary patients with a decreased chance of survival as the mucosal barrier is lost due to resultant tissue hypoxia, inflammation, and cellular infiltration [60,62]

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Although not yet fully understood, the glutathione injections may interfere with the normal functioning of hormones that regulate metabolism which can result in weight gain

At higher doses, the vial empties quickly, making larger vials more practical and cost-effective