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The latter is a competitor of 2-Oxoglutarate-dependent dioxygenases such as Ten-eleven translocation methylcytosine dioxygenase and therefore induces DNA hydroxymethylation and gene upregulation 52

GHK-Cu was also shown to play a role in ischemic and diabetic wound healing in rats, as well as decreasing TNF-alpha levels and increasing collagen synthesis ( Anti-Inflammatory Effects of GHK-Cu As it was mentioned above, GHK-Cu is shown to have antioxidant and anti-inflammatory properties