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In both in vitro and in vivo studies, Epitalon treatment is associated with increased TERT expression, elevated telomerase enzymatic activity (TRAP assay), and measurable preservation of telomere length as assessed by quantitative-FISH (Q-FISH) and Southern blotting of terminal restriction fragments (TRF)

These compounds sit in a gray zone: they are legal to sell and own for laboratory research, but they are not approved by the FDA for human use and are not dietary supplements

S-Acetyl-L-glutathione (6.25 g/g per day), but not GSH, increases survival in a mouse model of HSV-1 infection

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