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While emphasizing that e-cigarettes are not harmless for nonsmokers, the FDA and NIH recognize they could be a form of harm reduction and have called for more clinical trials into the safety and effectiveness of e-cigarettes as an aid in smoking cessation

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When the 2009 Tobacco Control Act prohibited the use of modified risk health descriptors such as light, mild, or low tar in cigarettes, Marlboro circumvented the rule by changing the names of their Marlboro Light cigarettes to Marlboro Gold, while Marlboro Ultra Lights became Marlboro Silver and Marlboro Mild was renamed Marlboro Blue