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The differing toxicities of ionizable organic compounds at different pH values can be attributed to the distinct permeabilities of the existing species (i.e., neutral and ionized forms) because neutral species can permeate biomembranes and become trapped in cells faster than the corresponding charged species, resulting in distinct differences in the internal concentrations

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From undisclosedComments about Vitamin B-12 1000mcgMy vet has me administering 1x per week for 6 weeks then once a month