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Among these, esculetin (ESC), a naturally occurring coumarin derivative also known as 6,7-dihydroxycoumarin, distinguishes itself by a comprehensive spectrum of biological activities

Antiviral activity of phenformin in vivo Given that phenformin is an established drug in humans with known pharmacokinetics and safety profiles, that is hence readily available, we further evaluated the in vivo antiviral potential of phenformin against SARS-CoV-2 in a Golden Syrian hamster model of infection (Fig

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R., Chakrabarti, K., King, G