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Serious symptoms are uncommon but need medical attention, including significant swelling, chest pain, shortness of breath, sudden vision changes, allergic reaction symptoms, or major mood changes

To correct for this, we performed RNA-seq analysis of hypothalami obtained from animals treated with daily injections of either GLP-1MK-801 or a dose of semaglutide that was equipotent in terms of weight-lowering efficacy over 5 days of treatment, that is, mice had achieved a comparable weight loss and reduction in food intake as that of GLP-1MK-801-treated mice (Extended Data Fig

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Das geht aus einem Artikel im Fachjournal JAMA Dermatology hervor, den ein Team um Mihir K