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While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker, L-NAME (prothrombotic) and the NOS-substrate L-arginine (antithrombotic), were little investigated

Astrocytes are also involved in the recruitment of inflammatory cells to the site of injury, through the formation of a glial scar termed reactive astrogliosis which involves activation and proliferation of astrocytes to limit extending damage (Lananna et al., 2018)