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Furthermore, a study revealed that tunicamycin administration in the ER caused a significant increase in cell death exclusively in wild-type mice and that administering antioxidants prior to angiotensin II prevented ER stress and apoptosis in cultured cardiac cells

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Consoli U, El-Tounsi I, Sandoval A, Snell V, Kleine HD, Brown W, Robinson JR, DiRaimondo F, Plunkett W, Andreeff M

The small second-order rate constant for the simulated reaction between GSH and the complex of reduced PfGrx C88S and roGFP2 WT (S 2 ) might reflect a poor accessibility of the 1st glutathione interaction site in this complex (Fig