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Until 1925~1926, the cigarette lighter officially became an automobile equipment in the United States

The countrys market-based approach to encouraging smokers to quit, however, has had both bright and dark sides

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Discussion In this nationwide population-based cohort study of more than 12 million live births in the USA, we found that maternal cigarette smoking, even at a low intensity (15 cigarettes per day), before pregnancy or during each trimester of pregnancy significantly increased the risk of six specific subtypes of congenital anomalies (i.e., congenital diaphragmatic hernia, gastroschisis, limb reduction defect, cleft lip with or without cleft palate, cleft palate alone, and hypospadias)