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Importantly, GDH1 knockdown elicited more pronounced inhibition on in vivo tumor growth, as shGDH1 Huh7 cells failed to grow into detectable xenografts and shGDH1 H1299 xenografts grew much more slowly than the control cohort (Extended Data Fig

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Regulated by the estrogen receptor and androgen receptor, respectively, MBOAT1/2 suppress ferroptosis by modifying phospholipids, presenting a distinct regulatory mechanism independent of GPX4 or FSP1 (Liang et al., 2023)

Meyer AJ, Rausch T (2008) Biosynthesis, compartmentation and cellular functions of glutathione in plant cells