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Trading in a regular cigarette for an electronic option could have significant health implications considering smoking cigarettes remains the leading cause of preventable death in the U.S

Jha et al estimated that on the basis of current rates of smoking initiation and cessation, smoking, which killed about 100 million people in the 20th century, will kill about 1 billion in the 21st century. Smoking harms women and men equally It had been thought that women were somehow less affected than men by tobacco smoke

In 2025, 1.4 million students reported current e-cigarette use, and among youth e-cigarette users, 27.5% reported using e-cigarettes daily

Pharmacotherapy choice will depend on previous experience, preference and whether or not the person will also consult a medical practitioner for a prescription