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The feasibility, safety, and tolerability of inosine have been shown in increasing UA levels in patients with ALS [137]

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Furthermore, we also found that 9 KOs encoding for molecules involved in the biosynthesis of the PGN ( dacC , mrcA , murA , murB , murE , murN , pbp2B , pbp2X , vanY ) and 10 encoding for quorum sensing molecules ( livK , secA , secG , secY , yidC , spo0A , agrC , ciaR , oppA , nisR ) were less abundant in birds wither BWG, together with KOs encoding for molecules involved in phosphotransferase system, protein export, glycerolipid metabolism, fatty acid biosynthesis, mismatch repair, vancomycin resistance, cell cycle ( dnab , clpx and ftsw )