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It was a dazzling display of ceremony and splendour, bringing true warmth to a nation that had become weary with war and austerity She was joined by eight bridesmaids, including her sister, Princess Margaret, her cousins, Princess Alexandra of Kent and Margaret Elpinstone, Philip's cousin, Pamela Mountbatten and her niece, Diana Bowes-Lyon

ensuring optimal use of resources given a lack of existing experimental evidence regarding an estimate of the effect and an uncertain estimate of the standard deviation of the primary outcome [18]