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However, specific studies on the roles of these key molecules at different stages of DOR progression are still lacking

doi: 10.1038/s41392-024-02107-5

F.HellwegC.WattS.WattT.BarschA.et al (2016)

These findings may inform appropriate expectation setting for patients and clinicians and highlight the need for better methods of treatment selection for patients with degenerative lumbar spinal stenosis. Surgery caused adjacent segment disease A December 2025 study ( 20 ) explained that lateral lumbar interbody fusion (LLIF) works by indirectly providing decompression by restoring disc height