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Many protocols begin immediately after surgery when healing begins

As can be seen in Supplementary Table 4, Te lengthened considerably more than Ti at the + 5 min time-point such that the Ti/Te ratio fell dramatically (-37 5%)

When severed nerves in animal models were placed in collagen tubes impregnated with GHK, researchers observed significantly increased nerve outgrowth, elevated production of nerve growth factor (NGF) and neurotrophins NT-3 and NT-4, accelerated regeneration of nerve fibers, and increased axon count and Schwann cell proliferation compared to controls

Its usually short-lived, but it can be really tough for those who experience it