So-called energy currency [177] refers to the molecule of nucleotide coenzyme adenosine triphosphate (ATP), which is the most exergonic source of chemical energy for use and storage in all cells, particularly in brain cells, to drive numerous endergonic processes, including biosynthesis, movement, ion transport, muscle contraction, nerve impulse propagation, intracellular signaling, and substrate phosphorylation [177]
NAD+ affects at least six hallmarks of aging through sirtuin activation, including DNA repair, mitochondrial function, epigenetic maintenance, nutrient sensing, autophagy, and stem cell function
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Annals of Oncology