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The researchers created their own calculation by looking at the number of cigarettes sold annually in the U.S., the number of people who died annually from smoking in the U.S., and the number of people who died annually in China from hazardous air exposure

Sample size calculation The required sample size was estimated to be 363 (min 272) based on the prevalence of IBS in the general population being estimated to be 13% with an estimated error of 4%, Type 1 error (alpha) 5% (two-tailed), power 95%, and allowing for a 25% dropout rate

At the beginning of October the straight-talking brand from British American Tobacco (BAT UK), Royals, will reveal a brand new pack