Following induction by LPS, CBD attenuated IL-8 and MCP-1 production but at the basal level, CBD induced the production of IL-8, CXCL1, Serpin E1, IL-6, IFN-y, MCP-1, RANTES, and TNF-, indicating that the effects of CBD may depend on the activation state [118] or anatomical location of the cells
These best practices are grounded in the case study authors' experiences and supplement those top-down principles enumerated in works such as ISO/TR 12300:2014 International Organization for Standardization: Health Informatics - Principles of Mapping between Terminological Systems
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