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Recent studies demonstrated that FUN14 domain containing 2, a mitochondrial protein which is upregulated in human hepatocellular carcinoma, interacted with and inhibited the GTPase domain of MFN1, resulting in the suppression of mitochondrial fusion

Inborn errors that may mimic Reyes syndrome include fatty-acid oxidation defects, amino and organic acidopathies, urea-cycle defects, and disorders of carbohydrate metabolism

The modification involves two specific changes: N-acetylation at the peptide's N-terminus and amidation at its C-terminus

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