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While deletion of CCN2 in DP cells and outer root sheath cells shortened telogen phase and increased the number of HFs, loss of CCN2 in vivo resulted in increase in K15-positive epidermal stem cells with high -catenin protein level and -catenin-dependent reporter gene activity

If you are into chemistry (if not, we understand, just skip this paragraph), the reason is that electrolytes (you know, the Na+ and Cl- ions) screen the electrostatic repulsion between the head groups of ionic surfactants and thus support the formation of long shaped micelles (instead of spherical ones) that entangle like spaghetti, and viola, a gel is formed

In addition, the applicability of these findings to older adults, patients with multimorbidity, or those with long-standing disease remains uncertain

Guidelines for growth hormone and insulin-like growth factor-I treatment in children and adolescents: growth hormone deficiency, idiopathic short stature, and primary insulin-like growth factor-I deficiency