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doi: 10.1038/s41523-020-00212-6 76 TuomistoAEMakinenMJVayrynenJP

Thus, we determined ER-stress response genes Xbp1 and the ER chaperone heat shock 70 kDa protein 5 (HSPA5, previously known as immunoglobulin heavy chain binding protein [BIP]), inflammation-responsive genes IL6 and IL1, and hypoxia-responsive genes hypoxia-inducible transcription factor 1 (HIF1) and GAPDH

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Topical Estrogen and Skin Aging Clinical studies suggest that topical estrogen improves skin elasticity, hydration, and dermal thickness in estrogen-deficient skin